How does melanocytes developed into cancerous cell?

Genetic factor and behavioral activities like tanning will cause a normal melanocyte become malignant (cancerous).

Ultraviolet (UV) sun damage is one of the most important contributors to melanoma. Cells that have been over exposed to sunburns during childhood or tanning bed will stand a high chance to become cancerous. The thinning of the ozone layer or clothing styles that expose larger skin area to sunlight also may contribute to a person's risk of skin cancer.

Researchers found that certain risk factors increase a person's chance of developing melanoma, including:

•a fair complexion (light skin that freckles or burns easily, blue eyes, or blond or red hair)

•multiple moles (typically more than 25)

•UV light exposure (whether from the sun or a tanning bed)

•a history of frequent or severe sunburns

•a relative with melanoma or a family history of irregular moles

•age (older people are at greater risk)

•a previous melanoma (a person who's had melanoma once is more likely to have a recurrence)